Selecting diagnostic tests for ruling out or ruling in disease: the use of the Kullback-Leibler distance

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Selecting diagnostic tests for ruling out or ruling in disease: the use of the Kullback-Leibler distance.

BACKGROUND To select a proper diagnostic test, it is recommended that the most specific test be used to confirm (rule in) a diagnosis, and the most sensitive test be used to establish that a disease is unlikely (rule out). These rule-in and rule-out concepts can also be characterized by the likelihood ratio (LR). However, previous papers discussed only the case of binary tests and assumed test ...

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ژورنال

عنوان ژورنال: International Journal of Epidemiology

سال: 1999

ISSN: 0300-5771,1464-3685

DOI: 10.1093/ije/28.3.521